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The name of your medicine is APO-simvastatin. It contains the active ingredient, simvastatin, which helps lower cholesterol
and triglyceride levels.
Simvastain is used by people who have coronary heart disease (CHD) or who are at high risk of CHD (for example, if they have
diabetes, a history of stroke, or other blood vessel disease).
This medication may be used, regardless of cholesterol level to:
help prolong life by reducing the risk of a heart attack
reduce the risk of stroke
reduce the need for surgery to increase blood flow to the heart
reduce the need for hospitalisation due to angina.
Cholesterol:
Everyone has cholesterol and triglycerides in their blood. They are types of blood fat needed by the body for many things,
including building cell walls, making bile acids (which help to digest food) and certain hormones. However, too much cholesterol
can be a problem. Your body makes cholesterol, but it also comes from food.
Normally the body balances the cholesterol it makes with the cholesterol it gets from food. This means if more cholesterol
comes from food, less is made by the body. However, if you eat a diet high in fat, your body may not keep this balance and
your cholesterol levels rise.
High cholesterol is more likely to occur with certain diseases or if you have a family history of high cholesterol.
When you have high levels of cholesterol, it may 'stick' to the inside of your blood vessels instead of being carried to the
parts of the body where it is needed. Over time, this can form hard areas, called plaque, on the walls of blood vessels, making
it more difficult for the blood to flow. This blocking of your blood vessels can lead to coronary heart disease (such as heart
attack and angina), and stroke.
In people with CHD, simvastatin may slow down the hardening of blood vessels and reduce the risk of developing new plaques.
There are different types of cholesterol, called LDL and HDL cholesterol. LDL cholesterol is the 'bad' cholesterol that can
block vessels. HDL cholesterol, on the other hand, is the 'good' cholesterol that is thought to remove the bad cholesterol
from the blood vessels.
Triglycerides:
Triglycerides are an energy source for the body. However, as with cholesterol, too much triglycerides can be a problem.
How it works
Simvastatin belongs to a group of medicines known as HMG-CoA reductase inhibitors. It works by reducing the amount of cholesterol
made by the liver. In terms of good and bad cholesterol, simvastatin reduces the bad cholesterol and raises the good cholesterol.
Simvastatin does not reduce the cholesterol and triglycerides that come from fat in food. Therefore, when you are taking simvastatin
you also need to follow a low fat diet and other measures, such as exercise and weight control.In most people, there are no
symptoms of high cholesterol or triglycerides. Your doctor can measure your cholesterol and triglycerides with a simple blood
test.
Your doctor may have prescribed simvastatin for another reason.
Ask your doctor if you have any questions about why this medicine has been prescribed for you.
This medicine is available only with a doctor's prescription.
This medicine is not addictive.
Use in children
This medicine is not recommended for use in children, as there have been no studies of its effects in children under the age
of 10 years.
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